PT-OPENSCREEN
National Infrastructure for Chemical Biology and Genetics
Reference:
NORTE-01-0145-FEDER-085468
Research Group:
Translating Life
CBMA Principal Investigator:
Funding Agency:
Fundo Europeu de Desenvolvimento Regional
Abstract
PT-OPENSCREEN is a nationwide network of chemistry and biology research institutes bridging chemistry-based research areas (organic and medicinal chemistry) and molecular and structural biology. It aims to operate a state-of-the-art infrastructure for basic and applied research in the fields of drug discovery, chemical biology and genetics. Across its partners provides Open Access synthesis of chemical tools and probes, cellular and biochemical assays for screening, as well as hit to lead, lead optimization and follow-up studies. A goal to achieve is to build a library of Portuguese chemical compounds. In addition, it coordinates the participation of Portugal in the Pan‐European ESFRI infrastructure EU‐OPENSCREEN, accessing the European Chemical Biology Library.
Status:
Concluded
Start / End:
06/2021 - 05/2023
CBMA Funding:
183 192,00 €
Website:
https://pt-openscreen.pt/
Research Team
Maria João Sousa; Susana Chaves; Manuela Côrte-Real; Isabel João Silva
Partners
Centro de Biologia Molecular e Ambiental (CBMA)
Centro de Biotecnologia dos Açores (CBA)
Centro de Engenharia Biológica da Universidade do Minho (CEB-UM)
Centro de Estudos de Doenças Crónicas (CEDOC)
Centro de Investigação de Engenharia Química e Biotecnologia (CIEQB)
Centro de Investigação em Química da Universidade do Porto (CIQUP)
Centro de Neurociências e Biologia Celular (CNC)
Centro de Química da Madeira (CQM)
Centro de Química da Universidade do Minho (CQUM)
Centro de Química de Coimbra (CQC)
Centro de Química Estrutural (CQE)
Centro de Toxicogenómica e Saúde Humana (ToxOmics)
Centro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR)
Instituto de Biomedicina – Aveiro (iBiMED)
Instituto de Biosistemas & Ciências Integrativas (BioISI)
Instituto de Higiene e Medicina Tropical (IHMT)
Instituto de Investigação do Medicamento (iMed.ULisboa)
Instituto de Investigação em Ciências da Vida e Saúde (ICVS)
Instituto de Medicina Molecular (iMM)
REMSENS
Remediation and sensing solutions for persistent pollutants decontamination
Reference:
FCT-DAAD | REMSENS
Coordinator:
CBMA
Research Group:
CBMA Principal Investigator:
Funding Agency:
FCT
Abstract
Water pollution is one of humanity's most important environmental problems. The most pressing issues arise from pharmaceuticals (e.g. diclofenac) due to their persistence in the aquatic environment. This project proposes a solution for the remediation of diclofenac. PVDF photocatalytic membranes will be produced to remove diclofenac as well as validated by ecotoxicity tests. Plasmonic sensors for diclofenac monitoring will also be developed.
Status:
Ongoing
Start / End:
01/2022 - 03/2024
CBMA Funding:
8 000,00 €
Website:
CBMA Research Team
Partners
Universidade do Minho (UMinho) (Coordenadora); Fraunhofer-Institut für Keramische Technologien und Systeme IKTS
RIPARIANET
Prioritising riparian ecotones to sustain and connect multiple biodiversity and functional components in river networks
Reference:
DivProtect/0010/2021
Coordinator:
CBMA - University of Minho
Research Group:
Sustaining
CBMA Principal Investigator:
Funding Agency:
FCT
Abstract
Conservation policy in river basins still do not account for the geometry of riparian networks, hindering their capacity to sustain adequately regional biodiversity. The RIPARIANET project emerges to provide novel insight for identify resilient floodplain systems. Main goals are: Remotely identify conservation hotspots; Provide a ground-proof quantifying riparian biodiversity and functioning; Translate this novel insight into an assisting tool for floodplain systems for multiple stakeholders.
Status:
Ongoing
Start / End:
04/2023 - 03/2026
CBMA Funding:
79 946,00 €
Website:
https://riparianet.eu/
CBMA Research Team
Partners
Rheinland-Pfälzische Technische Universität (Germany),Fondazione Edmund Mach (Italy),
University of Roma Tre (Italy),
FUNDACIÓN INSTITUTO DE HIDRÁULICA AMBIENTAL DE CANTABRIA (Spain),
Umeå University (Sweden)
River2Ocean
Socio-ecological and biotechnological solutions for the conservation and valorisation of aquatic biodiversity in the Minho Region
Reference:
NORTE-01-0145-FEDER-000068
Coordinator:
Universidade do Minho
CBMA Principal Investigator:
Fernanda Cássio
Funding Agency:
CCDR-N – Norte 2020, PORTUGAL2020, ERDF
Abstract
The River2Ocean project aims to develop socio-ecological and biotechnological solutions to promote biodiversity and aquatic ecosystem services in the Minho region, using an integrative approach from the river basins to the coast. This is a pioneer study for the Minho region, where an integrated assessment of biodiversity and habitats from catchment to coast will be performed.
Status:
Concluded
Start / End:
April 2021 - March 2023
CBMA Funding:
587 930,50 €
Website:
-
Research Team
-
Partners
-
SELFAQUASENS
Advanced manufacturing of self-sensing bio-based membranes for environmental detoxification and revalorization
Reference:
101131379 — SELFAQUASENS
Coordinator:
Fundación BCMATERIALS - Basque Center for Materials, Application and Nanostructures
Research Group:
Translating Life
CBMA Principal Investigator:
Funding Agency:
European Commission
Abstract
SELFAQUASENS project will develop a modular self-sensing filter and membrane technology able to: (I) remediate heavy metals and salinity pollutions in mining water, (II) couple the remediation to the recovery of CRE and (II) sense the concentration of specific elements or groups of elements during the process.
Status:
Ongoing
Start / End:
01/01/2024 - 31/12/2027
CBMA Funding:
795,800.00 €
Website:
-
CBMA Research Team
Pedro Martins
Partners
Fundación BCMATERIALS - Basque Center for Materials, Application and Nanostructures (Coordenadora);Universidad de Huelva (UHuelva);
Universidad de Chile;
UNIVERSIDAD DE BUENOS AIRES;
United Kingdom Research and Innovation;
Wise4Automation, Lda;
University of the Free State - Microbial biochemical and food biotechnology;
UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA (UPV-EHU);
Proteinmat materials SL;
ENERGIATUDOMANYI KUTATOKOZPONT
Smart4Vir
Smart surfactant-based nanovectors for RNA anti-viral therapeutics
Reference:
2022.05543.PTDC
Coordinator:
Faculdade de Ciências da Universidade do Porto (FC-UP)
Research Group:
CBMA Principal Investigator:
Funding Agency:
FCT
Abstract
This project proposes a bottom-up, holistic approach to develop efficient colloidal nanovectors that can deliver therapeutic RNA for anti-viral treatments. Novel ionizable, cleavable and biocompatible surfactants will be chemically synthesized to create rationally designed formulations, that will be characterized and tested for their capacity to encapsulate/compact different types of RNA. The most promising RNA/nanovectors will then be validated in experimental cell models.(DOI: 10.54499/2022.05543.PTDC)
Status:
Ongoing
Start / End:
02/2023 - 01/2026
CBMA Funding:
60 724,40 €
Website:
-
CBMA Research Team
Partners
Faculdade de Ciências da Universidade do Porto (FC-UP)REQUIMTE - REDE DE QUÍMICA E DE TECNOLOGIA
STREAMECO
Biodiversity and ecosystem functioning under climate change: from the gene to the stream
Reference:
POCI-01-0145-FEDER-031245
Coordinator:
CBMA
Research Group:
CBMA Principal Investigator:
Funding Agency:
FCT
Abstract
The goal of the STREAMECO project is to better understand how biodiversity and ecosystem functioning respond to multiple stressors related to climate change by incorporating functional traits and species evolution.
Status:
Concluded
Start / End:
01/06/2018 - 31/05/2022
CBMA Funding:
199 147,02 €
Website:
Research Team
Cláudia Pascoal; Fernanda Cássio; Ricardo Duarte; Isabel Fernandes; Giorgio Pace; Daniela Batista; Francisco Carvalho
Partners
Universidade do Minho (UMinho) (Coordenadora); Universidade de Coimbra (UC)
SuberControl
Influence of endosphere microbiome to control diseases in cork oak
Reference:
POCI-01-0145-FEDER-028635
Coordinator:
CBMA
Research Group:
Growing Life
CBMA Principal Investigator:
Funding Agency:
Fundo Europeu de Desenvolvimento Regional
Abstract
A severe decline on cork oaks has been strongly associated with drought stress conditions. Pathogens and other biotic stresses are described to cause cork oak decline, but their efficiency is far more enhanced in drought stressed trees. The main goal of this project is the identification of fungal endophytes (EF) that can play an effective role on Q. suber forest sustainability in a climate changing scenario.
Status:
Concluded
Start / End:
25/07/2018 - 24/04/2022
CBMA Funding:
178 613,15 €
Website:
Research Team
Teresa Lino Neto
Rui Tavares
Pedro Santos
Manuela Costa
Partners
Instituto Politécnico de Bragança - IPB (Portugal)
VINNY
Advanced nano encapsulation of bio-based pesticides and fertilisers for a circular and sustainable viticulture
Reference:
Horizon Europe - Grant Agreement number 101130039
Coordinator:
Centre for Microelectromechanical Systems (CMEMS), University of Minho
Research Group:
CBMA Principal Investigator:
Funding Agency:
European Commission
Abstract
The VINNY project aims to develop sustainable, low-cost nanoformulated biopesticides (nanoBPs) and biofertilisers (nanoBFs) to contribute to more resilient viticultural systems. The application of nanoformulations will contribute to the definitive shift from intensive to sustainable agriculture in viticulture on a global scale. This goal will be achieved using natural-based green circular economy concepts, through: 1. a holistic approach to vine physiology, where metabolites and bioactives based on the microbiome of different vineyards in Europe (Portugal, Spain, Austria and Denmark) will be studied to form potent cocktails with antifungal and phytopharmaceutical properties and 2. industrial by-products, NPK-rich actives from sludge from local wastewater treatment plants and the meat industry, to be used as biofertilisers.
Status:
Ongoing
Start / End:
CBMA Funding:
535 374,60 €
Website:
https://www.projectvinny.eu/
CBMA Research Team
Hernâni Gerós;Viviana Martins;
Partners
Universidade do Minho (UMinho) (Coordenadora); OSM Dan Ltd;
Associação para o desenvolvimento da viticultura duriense-ADVID;
University of Milano Bicocca (UNIMIB);
CNRS - Université de Tours;
Universidad Politécnica de Cataluña (UPC);
UNIVERSITAET FUER BODENKULTUR WIEN (BOKU);
InnovPlantProtect (InPP);
BORNHOLMS SPILDEVAND A/S;
PROJECT SAS DI MASSIMO PERUCCA;
ASOCIACION DE INVESTIGACION DE LA INDUSTRIA TEXTIL;
GLOBALWISE LTD;
HOHERE BUNDESLEHRANSTALT UND BUNDESAMT FUR WIEN-UND OBSTBAU;
PUBLIC DOMAIN UNIPESSOAL;
Ryp Labs;
DAVO STAR IMPEX SRL;
OCEAN CITY ApS;
Toni Beneito S.L