24/02/2025

UMinho Identifies Key Genes in Wine Yeasts

Unlocking the Potential of Non-Conventional Wine Yeasts

A research team from the Centre of Molecular and Environmental Biology (CBMA) at the University of Minho has characterized 530 wine yeast genomes, uncovering their crucial role in flavor, aroma, and fermentation. The study, published in Studies in Mycology, highlights the adaptability of non-Saccharomyces yeasts to climate change and evolving market demands.

The Role of Yeasts in Winemaking

Yeasts play a fundamental role in the winemaking process by converting grape sugars into alcohol while also producing key compounds that influence the final taste and aromatic profile of wine. While Saccharomyces cerevisiae is traditionally used in fermentation, growing evidence suggests that non-conventional non-Saccharomyces yeasts bring additional complexity and benefits to wine production.

Key Genetic Discoveries: The Fermentome and Flavorome

By analyzing 134 different species, researchers identified specific genetic markers associated with fermentation efficiency (termed the fermentome) and taste and aroma enhancement (the flavorome). These discoveries provide a genomic roadmap to optimize wine quality and address shifting consumer preferences.

Fermentome: A set of six key genes responsible for strong fermentation performance. Flavorome: A collection of 96 genes across 19 categories influencing wine aroma and flavor.

Applications for Winemakers and the Industry

This research opens up new possibilities for winemakers to fine-tune fermentation by selecting yeast strains with desirable genetic traits. In a changing climate, yeast adaptability is more crucial than ever. With genomic analysis, winemakers can:

Predict yeast performance in different climates ✅ Select strains for unique flavor profiles ✅ Enhance fermentation efficiency and stability  ✅ Ensure wines meet evolving market demands

Global Impact and Open Science

“The wine industry faces unprecedented challenges due to climate change and evolving consumer preferences. Our findings provide a scientific foundation for innovative and sustainable winemaking,” explains Ricardo Franco-Duarte, lead researcher.

All 530 analyzed genomes have been made freely available via the Data RepositóriUM of the University of Minho, ensuring open access for further research. The bioinformatics pipeline developed in this study also sets a new standard for yeast genomics, applicable beyond winemaking to industries such as brewing, baking, ecology, and clinical microbiology.

Read the full press release in portuguese HERE .

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