Exosomes are natural vesicles that mediate intercellular communication and have emerged as promising drug delivery vehicles. However, their clinical application is limited by scalability and heterogeneity. This project aims to engineer fully artificial exosomes for customizable delivery of bioactive molecules, including RNA. Additionally, we will adapt them for nose-to-brain delivery using a spray-dried formulation, enabling non-invasive and efficient transport of therapeutics to the brain.
