Vanessa Magalhães

Vanessa Magalhães

vamagalhaes@bio.uminho.pt

People Detail

Address : CBMA, Department of Biology, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal

Research Area : Biodiversity

Position : Integrated members

Qualifications

PhD in Biomedical Sciences (Institute of Biomedical Sciences Abel Salazar, ICBAS, University of Porto, Portugal) MSc in Clinical Immunology (Faculty of Health Sciences, University of Beira Interior, Covilhã, Portugal) BSc in Biochemistry (Faculty of Sciences/ ICBAS, University of Porto, Portugal)

Research

Currently working on an integrative approach that combines in vitro (biochemistry and cell culture) and in vivo assays using animal models (expected) to investigate the several bioactivities (antioxidant, anti-inflammatory...) of a number of plant extracts and relate them with their chemical composition (HPLC-DAD). Goal: to provide innovative, effective and safe products, based on plant extracts with anti-inflammatory and antioxidant activities, that ultimately can be useful in the regulation of the vicious oxinflammation process occurring in several chronic diseases.

Ongoing Projects

INTERACT – Integrative research in environment, agro-chain and technology - line 4. Bioactives from vegetable crops, MAPs and natural co-products

Concluded Projects

“A proteogenomics approach towards the understanding of Staphylococcus epidermidis pathogenicity” - MOSTMICRO Research Unit project; ITQB (University NOVA, Lisboa);

"Host-parasite Co-evolution" (integrated program IC&DT - SAESCTN-PIIC&DT/1/2011) - Research Center in Biodiversity and Genetic Resources (CIBIO, University of Porto);

"Understanding the potential of lactic acid bacteria: Nutritional Benefits and improving security in cheese" - CITA-A (Research Centre of Agrarian Technologies, University of Azores)

Students

Jocélio Evaristo Francelino - Master in Molecular Biology, Biotechnology and Entrepreneurship in Plants (Department of Biology – School of Sciences - University of Minho): “Desenvolvimento e validação de cosmocêuticos derivados de Diospyros kaki” – academic year 2018/2019

Bruna Gabriela Araújo da Silva - Applied Biology degree, Department of Biology – School of Sciences - University of Minho - BSc final graduation work: Comparative study of the antioxidant and anti-inflammatory activities and HPLC profile of Lycium extracts after simulated in vitro gastrointestinal digestion – academic year 2018/2019

Ana Rita Guimarães Machado Vaz da Silva - Master in Biochemistry (Department of Biology – School of Sciences - University of Minho: “...” – academic year 2019/2020

Publications

Rita G. Rocha, Vanessa Magalhães, José V. López-Bao, Wessel van der Loo, Luis Llaneza, Francisco Alvares, Pedro J. Esteves, and Raquel Godinho, 2019. Different demographic scenarios in a large carnivore have alternate selection mechanisms to maintain adaptive diversity. BMC Evol Biol; 19: 90. doi: 10.1186/s12862-019-1420-5;

Vanessa Magalhães, Jocélio Evaristo Francelino e Alberto C.P. Dias, 2019. In vitro cytotoxicity and antioxidant activity of Diospyros kaki extracts using L929 cell line – Work presented in the #4 Jornadas Interact, 11th April 2019 – UTAD, Vila Real;

Vanessa Magalhães, Maria S. Alves, Ademar Silva-Filho, Alberto C.P. Dias – Comparative study of the cytoprotective effects of Baccharis trimera and Baccharis dracunculfolia in vitro against oxidative insults” - Work presented in the 66th GA congress (Society for Medicinal Plant and Natural Product Research) , 26-29 august 2018, Shangai, China;

Vanessa Magalhães, Rejaine Rios, Alberto C.P. Dias. Cytoprotective effect of Hyptis spp. extracts against oxidative insults 2018; Free Radical Biology & Medicine, vol. 120, supplement 1;

Vanessa Magalhães, Rejaine Rios, Alberto C.P. Dias 2018. Cytoprotective effect of Hyptis spp. extracts in vitro. Work presented in the IISASGEO (II Simpósio Internacional de Águas, Solos e Geotecnologias) – 17 & 18 may 2018 – UTAD, Vila Real (in livro de resumos do IISASGEO & III JORNADAS INTERACT, página 140);

Vanessa Magalhães, Joana Abrantes, Antonio J. Munõz-Pajares, Pedro J. Esteves. Genetic diversity comparison of the DQA gene in European rabbit (Oryctolagus cuniculus) populations. Immunogenetics. 2015; 67: 579. doi: 10.1007/s00251-015-0866-x);

Célia Silva, Marina Domingos-Lopes, Vanessa Magalhães, Daniela Freitas, Márcia Coelho, Henrique Rosa, Maria de Lurdes Dapkevicius, 2015. Latin-style fresh cheese enhances lactic acid bacteria survival but not Listeria monocytogenes resistance under in vitro simulated gastrointestinal conditions. J Dairy Sci. 98: 4377. doi: 10.3168/jds.2015-9420;

Silva, C. G.; Magalhães, V.; Freitas, D.; Coelho, M.; Domingos-Lopes, M.; Dapkevicius, M.L.E.; Rosa, H. J. D. 2014. Fresh cheese as a food carrier of probiotic strains enhances subsequent survival in the gastrointestinal tract. Work presented in the 11th Symposium on Lactic Acid Bacteria, August 31st-September 4th, 2014, Egmond aan Zee, Netherlands;

Vanessa Magalhães, Elva Bonifácio Andrade, Joana Alves, Adília Ribeiro, Kwang Sik Kim, Patrick Trieu-Cuot, Paula Ferreira, 2013. Group B Streptococcus hijacks the host plasminogen system to promote brain endothelial cell invasion. PLOS ONE 8, e63244. doi: 10.1371/journal.pone.0063244;

Vanessa Magalhães, Isabel Veiga-Malta, Maria Rosário Almeida, Marina Baptista, Adília Ribeiro, Patrick Trieu-Cuot, Paula Ferreira, 2007. Interaction with human plasminogen system turns on proteolytic activity in Streptococcus agalactiae and enhances its virulence in a mouse model. Microbes Infection 9: 1276. doi: 10.1016/j.micinf.2007.06.001;

Pedro Madureira, Marina Baptista, Marta Vieira, Vanessa Magalhães, Ana Camelo, Liliana Oliveira, Delfina Tavares, Patrick Trieu-Cuot, Manuel Vilanova, Paula Ferreira, 2007. Streptococcus agalactiae GAPDH is a virulence-associatedimmunomodulatory protein. The Journal of Immunology 178: 1379. doi: 10.4049/jimmunol.178.3.1379)