Sandra Paiva

Sandra Paiva

People Detail

Address : Department of Biology, University of Minho, Campus de Gualtar,

Phone Number : 965386082

Research Area : Molecular targets

Position : Integrated members


Alves R, Barata-Antunes C, Casal M, Brown AJP, Van Dijck P, Paiva S (2020). Adapting to survive: how Candida overcomes host-imposed constraints during human colonization. Plos Pathogens (accepted for publication).

Alves R, Kastora SL, Pinho E, Rodrigues CF, Silva S, Casal M, Brown AJP, Henriques M, Paiva S (2020). Transcriptional responses of Candida glabrata biofilm cells to fluconazole are modulated by the carbon source. npj Biofilms and Microbiomes. Jan 2020. DOI: 10.1038/S41522-020-0114-5.

Gomez-Varela AI, Stamov D, Miranda A, Alves R, Barata-Antunes C, Dambournet D, Drubin D, Paiva S, De Beule PAA (2020). Simultaneous co-localized super-resolution fluorescence microscopy and atomic force microscopy: combined SIM and AFM platform for the life sciences.
Scientific Reports. Jan2020. DOI: 10.1038/S41598-020-57885-Z.

Ribas D, Soares-Silva I, Vieira D, Sousa-Silva M, Sá-Pessoa J, Azevedo-Silva J, Viegas SC, Arraiano CM, Diallinas G, Paiva S, Soares P, Casal M. The acetate uptake transporter family motif "NPAPLGL(M/S)" is essential for substrate uptake. Fungal Genet Biol. 2018 Oct 16;122:1-10. doi: 10.1016/j.fgb.2018.10.001.

Oliveira-Pacheco J*, Alves R*, Costa-Barbosa A, Cerqueira-Rodrigues B, Pereira-Silva, Paiva S, Silva S, Henriques M, Pais C & Sampaio P (2018) The role of Candida albicans transcription fator RLM1 in response to carbon adaptation. Front. Microbiol. 9:1127. doi: 10.3389/fmicb.2018.01127 *both authors contributed equally to this work.

Alves R, Mota S, Rodrigues CF, Silva S, Brown AJ, Henriques M, Casal M and Paiva S. (2017). The carboxylic acid transporters Jen1 and Jen2 affect Candida albicans biofilm architecture and fluconazole susceptibility in the presence of lactate. Biofouling 33(10): 943-954.

Talaia G, Gournas C; Saliba E; Barata-Antunes C; Casal M; André B; Diallinas G; Paiva S. (2017). The α-arrestin Bul1p mediates the endocytic turnover of Jen1p lactate transporter in response to alkalinization and distinct physiological signals. Journal of Molecular Biology. 429(23): 3678-3695.

Ribas, D., Sá-Pessoa, J., Soares-Silva I., Nigard, Y., Paiva, S., Ryohonen, L., Pentillä, M., Casal, M. (2017). Yeast as tool to express sugar acid transporters with biotechnological interest. FEMS Yeast research. 1;17(2). doi: 10.1093/femsyr/fox005.

Casal M, Queirós O, Talaia G, Ribas D, Paiva S. (2016). Carboxylic Acids Plasma Membrane Transporters in Saccharomyces cerevisiae. Adv Exp Med Biol. 892:229-51. doi: 10.1007/978-3-319-25304-6_9.

Mota S, Alves R, Carneiro C, Silva S, Brown AJ, Istel F, Kuchler K, Sampaio P, Casal M, Henriques M and Paiva S (2015). Candida glabrata susceptibility to antifungals and phagocytosis is modulated by acetate. Front Microbiol 6:919. doi:10.3389/fmicb.2015.00919.

Soares-Silva I, Ribas D, Foskolou Z, Barata B, Bessa D, Queiros O, Paiva S, Casal (2015). The Debaryomyces hansenii carboxylate transporters Jen1 homologues are functional in Saccharomyces cerevisiae. FEMS Yeast Res 15.

Mota, S, Vieira N, Barbosa S, Delaveau T, Torchet C, Lesaux A, Garcia M, Pereira A, Lemoine S, Coulpier F, Darzacq X, Benard L, Tanner K, Banroques J, Casal M, Devaux F and Paiva S. (2014). Role of the DHH1 gene in the regulation of monocarboxylic acids transporters expression in Saccharomyces cerevisiae. PLOS ONE 9(11):e111589.

Lopes C, Fonseca P, Matamá T, Gomes A, Louro C, Paiva S, Vaz F. (2014). Protective Ag:TiO2 thin films for pressure sensors in orthopedic prosthesis: the importance of composition, structural and morphological features on the biological response to the coatings. J Mater Sci Mater Med 25(9):2069-81.

Sá-Pessoa J, Paiva S, Ribas D, Silva IJ, Viegas SC, Arraiano CM, Casal M. (2013). SATP (YaaH), a succinate-acetate transporter protein in Escherichia coli. Biochem J. 454(3):585-95.

Paiva S, Strachotová D, Kučerová H, Hlaváček O, Mota S, Casal M, Palková Z, Váchová L. (2013). The transport of carboxylic acids and important role of the Jen1p transporter during the development of yeast colonies. Biochem J. 454(3):551-8.

Teixeira S, Sá R, Grangeia A, Silva J, Oliveira C, Ferráz L, Alves A, Paiva S, Barros A and Sousa M. (2013). Immunohystochemical analysis of CFTR in normal and disrupted spermatogenesis Syst Biol Reprod Med. 59: 53-9.

Pacheco A, Talaia G, Sá-Pessoa J, Bessa D, Gonçalves MJ, Moreira R, Paiva S, Casal M, Queirós O. (2012). Lactic acid production in Saccharomyces cerevisiae is modulated by expression of the monocarboxylate transporters Jen1 and Ady2. FEMS Yeast Res. 12(3):375-81.

Becuwe M, Vieira N, Lara D, Gomes-Rezende J, Soares-Cunha C, Casal M, Haguenauer-Tsapis R, Vincent O, Paiva S*, Léon S*. (2012). A molecular switch on an arrestin-like protein relays glucose signaling to transporter endocytosis. J Cell Biol. 196(2):247-59. *These authors contributed equally to this work.

Vieira N, Pereira F, Casal M, Brown AJ, Paiva S and Johansson B. (2010). Plasmids for in vivo construction of integrative Candida albicans vectors in Saccharomyces cerevisiae. Yeast. 27(11):933-9.

Vieira N, Casal M, Johansson B, Maccallum DM, Brown AJ and Paiva S (2009). Functional specialization and differential regulation of short chain carboxylic acid transporters in the pathogen Candida albicans. Mol Microbiol 75(6):1337-54.

Paiva S, Vieira N, Nondier I, Haguenauer-Tsapis R, Casal M and Urban-Grimal D. (2009). Glucose-induced ubiquitylation and endocytosis of the yeast Jen1 transporter: role of k63-linked ubiquitin chains. J Biol Chem. 284: 19228-36.

Casal M, Paiva S, Queirós O. and Soares-Silva I. (2008). Transport of carboxylic acids in yeast. FEMS Microbiol Rev 32(6): 974-94.

Soares-Silva I, Paiva S, Diallinas G. and Casal M. (2007). The conserved sequence NXX[S/T]HX[S/T] QDXXXT of the Lactate/Pyruvate:H+ Symporter Subfamily, is critical for Jen1p kinetics and specificity. Mol Membr Biol 24: 464-474.

Queiros O, Pereira L, Paiva S, Moradas-Ferreira P. and Casal M. (2007). Functional analysis of Kluyveromyces lactis carboxylic acids permeases: heterologous expression of KlJEN1 and KlJEN2 genes. Curr Genet 51: 161-169.

Ramalho PA, Paiva S, Cavaco-Paulo A, Casal M, Cardoso MH and Ramalho MT. (2005). A key role of a plasma membrane redox system in the decolourization of azo dyes by the yeast Saccharomyces cerevisiae. Appl Environ Microbiol 71: 3882-8.

Soares-Silva I, Paiva S, Kotter P, Entian KD and Casal M. (2004). The disruption of JEN1 from Candida albicans impairs the transport of lactate. Mol Membr Biol 21: 403-411.

Paiva S, Devaux F, Barbosa S, Jacq C and Casal M. (2004). Ady2p is essential for the acetate permease activity in the yeast Saccharomyces cerevisiae. Yeast 21: 201-210.

Paiva S, Kruckeberg A L and Casal M. (2002). Utilization of GFP as a marker for studying the expression and turnover of JEN1 of Saccharomyces cerevisiae. Biochem J 363: 737-44.

Makuc J*, Paiva S*, Schauen M*, Krämer R, André B, Casal M, Leão C and Boles E. (2001). The putative monocarboxylate permeases of the yeast Saccharomyces cerevisiae do not transport monocarboxylic acids across the plasma membrane. Yeast 15: 1131-43. *These authors contributed equally to this work.

Casal M, Paiva S, Andrade R, Gancedo C e Leão C. (1999). The Lactate-Proton Symport of Saccharomyces cerevisiae is encoded by JEN1. J. Bacteriol 181: 2620-2623.

Paiva S, Althoff S, Casal M e Leão C. (1999). Transport of acetate in mutants of Saccharomyces cerevisiae defective in monocarboxylate permeases. FEMS Microbiol Lett 170: 301-306.