People Detail

Invited Assistant Professor. Ph.D. - Molecular and Environmental Biology (2017). MSc - Molecular Genetics (2011). BSc - Applied Biology (2008).

António Ribeiro (MSc, ongoing)

Chaves, S. R., Rego, A., Martins, V. M., Santos-Pereira, C., Sousa, M. J., & Côrte-Real, M. Regulation of Cell Death Induced by Acetic Acid in Yeasts. Frontiers in Cell and Developmental Biology (2021): 9, 642375.

Rego, António; Mendes, Filipa; Costa, Vítor; Chaves, Susana Rodrigues; Côrte-Real, Manuela. "Pkh1p-Ypk1p and Pkh1p-Sch9p Pathways Are Activated by Acetic Acid to Induce a Mitochondrial-Dependent Regulated Cell Death". Oxidative Medicine and Cellular Longevity (2020): 1-14.

Costa, Ana Rita; Machado, Nuno; Rego, António; Sousa, Maria João; Côrte-Real, Manuela; Chaves, Susana R.. "Proteasome inhibition prevents cell death induced by the chemotherapeutic agent cisplatin downstream of DNA damage". DNA Repair 73 (2019): 28-33.

Rego, António; Cooper, Katrina F.; Snider, Justin; Hannun, Yusuf A.; Costa, Vítor; Côrte-Real, Manuela; Chaves, Susana R.. "Acetic acid induces Sch9p-dependent translocation of Isc1p from the endoplasmic reticulum into mitochondria". Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1863 6 (2018): 576-583.

Acosta-Zaldívar, M.; Andrés, M. T.; Rego, António.; Pereira, C. S.; Fierro, J. F.; Côrte-Real,M.. "Human lactoferrin triggers a mitochondrial- and caspase-dependent regulated cell death in Saccharomyces cerevisiae". Apoptosis 21 2 (2015): 163-173.

Rego, Antonio; Duarte, Ana; Azevedo, Flavio; Sousa, Maria; Corte-Real, Manuela; Chaves, Susana. "Cell wall dynamics modulate acetic acid-induced apoptotic cell death of Saccharomyces cerevisiae". Microbial Cell 1 9 (2014): 303-314.

Rego, António; Trindade, Dário; Chaves, Susana R.; Manon, Stéphen; Costa, Vítor; Sousa, Maria João; Côrte-Real, Manuela. "The yeast model system as a tool towards the understanding of apoptosis regulation by sphingolipids". FEMSYeast Research 14 1 (2013): 160-178.

Pacheco, Andreia; Azevedo, Flávio; Rego, António; Santos, Júlia; Chaves, Susana R.; Côrte-Real, Manuela; Sousa, Maria João. "C2-Phytoceramide Perturbs LipidRafts and Cell Integrity in Saccharomyces cerevisiae in a Sterol-Dependent Manner". PLoS ONE 8 9 (2013): e74240.

Pereira, Helena; Azevedo, Flávio; Rego, António; Sousa, Maria João; Chaves, Susana R.; Côrte-Real, Manuela. "The protective role of yeast Cathepsin D in acetic acid-induced apoptosis depends on ANT (Aac2p) but not on the voltage-dependent channel (Por1p)". FEBS Letters 587 2 (2012): 200-205.

Rego, António; Costa, Margarida; Chaves, Susana Rodrigues; Matmati, Nabil;Pereira, Helena; Sousa, Maria João; Moradas-Ferreira, Pedro; et al. "Modulation of Mitochondrial Outer Membrane Permeabilization and Apoptosis by Ceramide Metabolism". PLoS ONE 7 11 (2012): e48571.