da Costa André

André Costa

andrecosta@bio.uminho.pt

People Detail

Address : CBMA, Department of Biology, University of Minho, Campus Gualtar, 4710-057 Braga

Research Area : Bio-Inspired Systems

Position : Integrated members

Qualifications

Junior Researcher at Fun2Cyt project. PhD in Molecular and Environmental Biology. MSc in Molecular Genetics and BSc in Biology.

Research

AREA OF CURRENT SCIENTIFIC ACTIVITY: - Molecular biology/biotechnology - Materials Science - Design and production of functional recombinant protein-based polymers - Materials with antimicrobial properties

Ongoing Projects

FUN2CYT. Harnessing the potential for biomedical applications of pleiotropic cytokines LIF and oncostatin M

Publications

• Correia D.M., Ribeiro S., da Costa A., Ribeiro C., Casal M, Lanceros-Mendez S. and Machado R. “Development of bio-hybrid piezoresistive nanocomposites using silk-elastin protein copolymers” – Composites Science and Technology. 2019. DOI: 10.1016/j.compscitech.2019.01.017.
• da Costa A., Machado R., Rodriguez-Cabello J.C., Gomes A.C. and Casal M. “Production of bioactive Hepcidin by recombinant DNA tagging with an elastin-like recombinamer” – New Biotechnology. 2018, 46, pp. 45-53. DOI: 10.1016/j.nbt.2018.07.001
• Fernandes M.M., Correia D.M., da Costa A., Ribeiro S., Casal M., Lanceros-Méndez S. and Machado R. “Multifunctional magnetically responsive biocomposites based on genetically engineered silk-elastin-like protein” Composites Part B: Engineering, 2018, 153, pp. 413-419. DOI: 10.1016/j.compositesb.2018.09.019
• Machado, R., da Costa, A., Silva, D. M., Gomes, A. C., Casal, M., Secandas, V. "Antibacterial and Antifungal Activity of Poly(Lactic Acid)–Bovine Lactoferrin Nanofiber Membranes" Macromolecular Bioscience. 2018, 18, 1700324. DOI: 10.1002/mabi.201700324
• da Costa, A., Pereira, A. M., Gomes, A. C., Rodriguez-Cabello, J. C., Sencadas, V., Casal, M., Machado, R.. “Single step fabrication of antimicrobial fibre mats from a bioengineered protein-based polymer”. Biomedical Materials. 2017. 12 (4), 045011-1-045011-11. DOI: 10.1088/1748-605X/aa7104
• Pereira A.M.*, Machado R.*, da Costa A., Ribeiro A., Bernardo C.T., Collins T., Gomes A.C., Leonor I.B., Kaplan D., Reis R.L., Casal M. “Silk-based polymers functionalized with fibronectin type II for improved cell adhesion” – Acta Biomaterialia, 2017 1;47:50-59 (*-equal contributors). DOI: 10.1016/j.actbio.2016.10.002
• Machado R., da Costa A., Sencadas V., Pereira A.M., Collins T., Rodríguez-Cabello J.C., Lanceros-Méndez S., Casal M. “Exploring the Properties of Genetically Engineered Silk-Elastin-Like Protein Films” Macromol. Biosci. 2015, 15 (12);1698-1709. DOI: 10.1002/mabi.201500132

da Costa A.*, Machado R.*, Ribeiro A., Thiagarajan V., Neves-Petersen M.T., Rodríguez-Cabello J.C., Gomes A.C., Casal M. “Development of elastin-like recombinamer films with antimicrobial activity” Biomacromolecules. 2015, 16 (2) DOI: 10.1021/bm5016706 (* - equal contributors)
• Machado R., da Costa A., Sencadas V., Garcia-Arévalo C., Costa C.M., Padrão J., Gomes A., Lanceros-Méndez S., Rodríguez-Cabello J.C., Casal M. “Electrospun silk-elastin-like fibre mats for tissue engineering applications”, Biomedical Materials. 2013; 8. DOI: 10.1088/1748-6041/8/6/065009
• Collins T.*, Azevedo-Silva J.*, da Costa A.*, Branca F., Machado R., Casal M. “Batch production of a silk-elastin-like protein in E. coli BL21(DE3): key parameters for optimisation”. Microb Cell Fact. 2013 Feb; 12(1):21. (* - equal contributors). DOI: 10.1186/1475-2859-12-21