People Detail
Address : University of Minho, Dep. Biology, Campus de Gualtar, Braga, Portugal
Phone Number : +351253604310
Research Area : Biodiversity
Position : Integrated members
Qualifications
Degree in Applied Biology (Univ. Lisbon, 1989), MSc in Biotechnology (IST 1993), PhD (UMINHO, 2001). Professor at University of Minho, since 1991. Presently he is coordinator of SINO-PT Center at IBs (CBMA/UMinho) and coordinator of AgroBioPlant Research group (ECUM, Uminho), and director of AgriChains, International FCT PhD program, in collaboration with UTAD (Vila Real, Portugal), Wagening University (Netherlands) and Univ. Politecnica de Valencia (Valencia, Spain)
Research
Study of plant secondary metabolites and their bioactivities, focusing on antioxidant, anti-inflammatory and neuroprotective properties. Development of added-value products incorporating byproducts and plant functional extracts, fractions or compounds in several matrices (nanoparticles, textiles, cosmetics, functional foods, phytopharmaceuticals).
Ongoing Projects
HealthKaki (QREN2020)
SkinHealth (QREN2020)
Extratoteca (QREN2020)
NEURO-SINO-PT (FCT China-PT project)
Ethnoherbs (Horizon 2020, EU)
Concluded Projects
(2015-ongoing) Interact-ISAC, INNOVATION FOR SUSTAINABLE AGRO-FOOD CHAINS (ISAC), Project 4. Bioactives from vegetable crops, MAPs and natural co-products; Structured R&D&I Projects, NORTE-45-2015-02
(2010-14) Functional foods for neuroprotection: a role to Hypericum perforatum (Hyperi-Food), PTDC/AGR-ALI/105169/2008; approved for funding by FCT; (PI: Alberto Dias)
(2008-2012) SEVENTH FRAMEWORK PROGRAMME THEME [FP7-HEALTH-2007-2.1.2-7; Coordination action, "Good Practice in Traditional Chinese Medicine Research in the Post-genomic Era"; Deputy of the project.
“Botryofuel – Microalgae hiper-producers of biofuel”, 2007-2008. ADI Project, POCI 2010-Ideia, Nº 13-05-04-FDR-00041. Participating member: A. Dias (UM).
Martec-Sea Technologies, Sub-project Algatec (2007-2008). PI: A. Dias; NITEC – Industry Contract Research with Necton, SA. Participating member: A. Dias (UM). (study of algae derived products with bioactivities)
“Study of Olea europea L. portuguesa defense response against Pseudomonas savastanoi” (2000-2005). POCTI/AGR/36239/99 (Participating member: A. Dias )
“Study of the mechanisms host-pathogen in ectomycorriza of Castanea sativa Mill.(Castanheiro europeu) ” (2001-2006)- POCTI/BSE/38059/2001 (Participating member: A. Dias (UM).)
“Isolation, cloning and functionality of genes related to salt tolerance in Populus euphratica” (2001-2006)- POCTI/AGR/38584/2001 (Participating member: A. Dias)
“Study of the defence mechanisms of Hypericum perforatum against Colletotrichum gloeosporioides (antracnose)” (2002-2007)- POCTI/AGR/40283/2001 (PI: A. Dias)
"Investigation of secondary metabolism in Hypericum perforatum and Arabidopsis thaliana induced by methyljasmonate and fungal elicitor.", bilateral Cooperation GRICES-DAAD (2005-07), with Prof. Erich Kombrink (Max Planck Institute, Cologne). (PI: Alberto Dias ).
“Study of the influence of Esca in the phenolic composition of the wines Verdes and Rias Baixas” (1998-2001)- bilateral Cooperation CSIC-ICCTI (proc. 423/Spain, with CEBAS, Prof. Federico Ferreres), (PI: Alberto Dias).
Publications
(2019). Xu, L., Burkin, M., Eremin, S., Dias, A.C.P., Zhang, X. “Development of Competitive ELISA and CLEIA for Quantitative Analysis of Polymyxin B”, Food Analytical Methods (in press). IF: 2,245
(2018). “Lipid nanocarriers loaded with natural compounds: Potential new therapies for age related neurodegenerative diseases? “, Prog Neurobiol. 168:21-41. doi:10.1016/j.pneurobio.2018.04.004. IF: 14,163
(2018). Oliveira A., Pinho C., Fonte P., Sarmento B., Dias ACP.. “Development, characterization, antioxidant and hepatoprotective properties of poly(Ɛ-caprolactone) nanoparticles loaded with a neuroprotective fraction of Hypericum perforatum”. International Journal of Biological Macromolecules. 110:185-196. doi: 10.1016/j.ijbiomac.2017.10.103; IF: 3,909
(2017). Marta R.M. Lima, Mafalda L. Felgueiras, Ana Cunha, Gisela Chicau, Federico Ferreres, Alberto C.P. Dias. “Differential phenolic production in leaves of Vitis vinifera cv. Alvarinho affected with esca disease”, Plant Physiology and Biochemistry 112, 45-52. http://dx.doi.org/10.1016/j.plaphy.2016.12.020. IF: 2,724
(2017). Gregory Marslin, Bruno Sarmento, Gregory Franklin, José Martins, Carlos Silva, Andreia Gomes, Marisa Passos Sárria, Olga Coutinho, Alberto C.P. Dias. “Curcumin Encapsulated into Methoxy Poly(EthyleneGlycol) Poly(ε-Caprolactone) Nanoparticles Increases Cellular Uptake and Neuroprotective Effect in Glioma Cells”. Planta Medica; 83: 434–444. DOI http://dx.doi.org/10.1055/s-0042-112030; IF: 2,342