Nanodanio Lab

Supervisor: Andreia Gomes

Zebrafish (Danio rerio) embryos are a powerful, alternative model for toxicity testing for in vivo assessment of new compounds and nanoparticles at an early stage in drug discovery. They offer the possibility to perform small-scale high-throughput screenings, due to their advantages such as rapid development, small size, easy maintenance, transparency and capacity to absorb compounds dissolved in the water. This facility permits to carry out the Zebrafish embryotoxicity (ZET) assay, recommended by the OECD for toxicity analysis and a valuable tool for assessing biocompatibility.